MOTS-C (20mg) vial
Currently unavailable

MOTS-C

20mg Lyophilised Powder

$125.99AUD per vial

Concentration

20mg

CAS Number

1627580-64-6

Volume Savings

1
Express shipping available Australia-wide
Independently laboratory tested for 99%+ purity

Currently unavailable

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Product Information

Your Body Made This Peptide. Now It Makes Less of It Every Year.

MOTS-C (20mg) will be available in Australia through Aus Peptide Supply with fast domestic shipping to all states and territories.

MOTS-C is a peptide your own mitochondria produce — and one of the most unusual molecules in longevity research because it doesn't come from your DNA like most proteins do. It comes from the mitochondria themselves. First identified by researchers at the University of Southern California in 2015, MOTS-C has rapidly become one of the most studied molecules in metabolic and anti-ageing science.

The pattern is familiar: your body produces less of it as you age, and that decline correlates with the metabolic problems that accumulate over time — worse insulin sensitivity, lower energy output, reduced exercise capacity. Researchers studying MOTS-C are asking whether restoring it can reverse some of these changes. Early data, particularly in animal models, is compelling.

The 20mg vial is the natural choice for longer protocols. You get twice the compound, better value per milligram, and fewer reorders interrupting a structured research plan.

What MOTS-C Is Studied For

  • Metabolic Health & Insulin Sensitivity — Studied for improving glucose uptake and insulin signalling — directly relevant to type 2 diabetes and metabolic syndrome research
  • Exercise Performance — Associated with improved endurance, exercise tolerance, and the body's adaptive response to training in preclinical models
  • Healthy Ageing & Longevity — Plasma MOTS-C levels decline with age and correlate with biological age markers — making it a focus of longevity researchers studying metabolic decline
  • Cellular Energy Balance — Acts as a cellular stress signal that activates the body's master energy regulator, improving how cells produce and use fuel
  • Obesity & Fat Metabolism — Studied in high-fat diet models for reversing insulin resistance and improving fat metabolism

Supplied as lyophilized powder at high purity, verified by HPLC and mass spectrometry. 20mg per vial. Fast domestic shipping across Australia, with batch-specific CoA information available in our CoA Library.

⚠ For in-vitro research and laboratory use only. Not for human consumption.

Frequently Asked Questions

What is MOTS-C?
MOTS-C is a peptide your mitochondria produce naturally — and one of the most unusual molecules in longevity research because it doesn't come from your nuclear DNA like most proteins do. It was discovered in 2015 by researchers at the University of Southern California. Its role is metabolic signalling: it tells your cells how to handle energy, glucose, and stress. Levels decline with age, and that decline correlates with the metabolic problems that tend to accumulate as people get older — insulin resistance, reduced exercise capacity, poor energy regulation.
Why choose the 20mg vial?
The 20mg vial is the better fit for longer research runs. You get twice the compound of the 10mg version, better value per milligram, and fewer interruptions from needing to reorder mid-protocol. If you already know MOTS-C is part of your research stack, the 20mg is simply more practical.
What makes MOTS-C different from other longevity peptides?
Most longevity peptides — Epitalon, GHK-Cu, SS-31 — either target gene expression, cell repair, or mitochondrial protection. MOTS-C is specifically a metabolic signal: it regulates how your body produces and uses energy at the cellular level. It's most relevant for researchers focused on metabolic health, insulin sensitivity, and exercise adaptation alongside longevity — rather than purely on skin, telomeres, or inflammation.
How does MOTS-C work?
When cells are under metabolic stress, MOTS-C moves from the mitochondria into the cell nucleus and activates the body's master energy-regulating switch — a protein called AMPK. When AMPK is active, cells take up glucose more efficiently, burn fat more readily, and generally run more cleanly. This is the same pathway that exercise activates — and researchers believe declining MOTS-C is part of why older bodies respond less effectively to the same training stimulus than younger ones.
What does the research show about MOTS-C?
Animal studies have shown MOTS-C can reverse high-fat diet-induced insulin resistance, improve exercise tolerance, and counteract age-related metabolic decline. In humans, circulating MOTS-C levels are lower in people with type 2 diabetes and obesity — and decline measurably with age — supporting the idea that it plays an active protective role rather than being a passive byproduct of healthy metabolism.
How do you reconstitute MOTS-C?
MOTS-C is supplied as a lyophilized powder and should be reconstituted with bacteriostatic water (BAC water) immediately before use. Inject the BAC water slowly into the vial, directing the stream down the inside wall. Gently swirl to dissolve — do not shake. Once reconstituted, store at 2–8°C and use within 28 days. For a full step-by-step walkthrough, see our complete peptide reconstitution guide.
How should MOTS-C be stored?
Store lyophilized MOTS-C vials at -20°C, away from light and moisture. After reconstitution with BAC water, refrigerate at 2–8°C and use within 28 days. Do not freeze the reconstituted solution.
Where to buy MOTS-C in Australia?
MOTS-C (20mg) will be available through Aus Peptide Supply with fast domestic shipping to all Australian states and territories. Every vial is dispatched from within Australia — no customs delays, no international freight uncertainty. Batch-specific CoA information will be available in our CoA library.
What is the availability and cost of MOTS-C?
MOTS-C (20mg) is currently out of stock at Aus Peptide Supply. MOTS-C (20mg) is priced at $125.99 per vial at Aus Peptide Supply. All orders ship domestically within Australia, and batch CoAs are available in our CoA library.

Purchase Other Quantities

MOTS-C is also available in other vial sizes. Compare the current formats below and jump straight to the quantity that fits your protocol.

MOTS-C (10mg)

PEP-014-10MG

$94.99

Currently unavailable

View this quantity →

MOTS-C (20mg)

PEP-029-20MG

Current

$125.99

Currently unavailable

Viewing this quantity →